Association between long-term adherence to class-I recommended medications and risk for potentially preventable heart failure hospitalizations among younger adults.

ABSTRACT: BACKGROUND:Five guideline-recommended medication categories are available to treat patients who have heart failure (HF) with reduced ejection fraction. However, adherence to these medications is often suboptimal, which places patients at increased risk for poor health outcomes, including hospitalization. We aimed to examine the association between adherence to these medications and potentially preventable HF hospitalizations among younger insured adults with newly diagnosed HF. METHODS AND RESULTS:Using the 2008-2012 IBM MarketScan Commercial database, we followed 26,439 individuals aged 18-64 years with newly diagnosed HF and calculated their adherence (using the proportion of days covered (PDC) algorithm) to the five guideline-recommended medication categories: angiotensin-converting enz

SUBMITTER: Chang TE 

PROVIDER: S-EPMC6756532 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature