Impact of the modality of mechanical ventilation on bleeding during pituitary surgery: A single blinded randomized trial.

ABSTRACT:

Background

Bleeding modifies the surgeon's view of the field during transsphenoidal endoscopic pituitary surgery. Since ventilation can alter venous return, we compared the effect of volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) on intraoperative bleeding.

Methods

Eighty-six patients were randomized to VCV or PCV in this single blinded study; comparisons concerned 42 in the PCV group and 43 in the VCV group.

Results

Intraoperative bleeding, the primary endpoint, did not differ between groups whether analysis focused on 7 levels of the score, from minimal bleeding to bleeding with significant change in the conduct of surgical procedure (P = .89) or on a stratification into 3 categories, mild, moderate, and major (P = .47). Median [interq

SUBMITTER: Le Guen M 

PROVIDER: S-EPMC6756699 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature