Protocolized Brain Oxygen Optimization in Subarachnoid Hemorrhage.

ABSTRACT:

Background

Brain tissue hypoxia (P_btO₂ < 20 mmHg) is common after subarachnoid hemorrhage (SAH) and associated with poor outcome. Recent data suggest that brain oxygen optimization is feasible and reduces the time spent with P_btO₂ < 20 mmHg from 45 to 16% in patients with severe traumatic brain injury. Here, we intended to quantify the brain tissue hypoxia burden despite implementation of a protocolized treatment approach in poor-grade SAH patients and to identify the simultaneous occurrence of pathologic values potentially amenable to treatment.

Methods

We present a bi-centric observational cohort study including 100 poor-grade SAH patients admitted to two tertiary care centers who underwent multimodal brain monitoring and were ma

SUBMITTER: Rass V 

PROVIDER: S-EPMC6757026 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature