Continuous photoproduction of hydrocarbon drop-in fuel by microbial cell factories.

ABSTRACT: Use of microbes to produce liquid transportation fuels is not yet economically viable. A key point to reduce production costs is the design a cell factory that combines the continuous production of drop-in fuel molecules with the ability to recover products from the cell culture at low cost. Medium-chain hydrocarbons seem ideal targets because they can be produced from abundant fatty acids and, due to their volatility, can be easily collected in gas phase. However, pathways used to produce hydrocarbons from fatty acids require two steps, low efficient enzymes and/or complex electron donors. Recently, a new hydrocarbon-forming route involving a single enzyme called fatty acid photodecarboxylase (FAP) was discovered in microalgae. Here, we show that in illuminated E. coli cultures coexpressi

SUBMITTER: Moulin S 

PROVIDER: S-EPMC6757031 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature