Roles of membrane transporters: connecting the dots from sequence to phenotype.

ABSTRACT:

Background

Plant membrane transporters are involved in diverse cellular processes underpinning plant physiology, such as nutrient acquisition, hormone movement, resource allocation, exclusion or sequestration of various solutes from cells and tissues, and environmental and developmental signalling. A comprehensive characterization of transporter function is therefore key to understanding and improving plant performance.

Scope and conclusions

In this review, we focus on the complexities involved in characterizing transporter function and the impact that this has on current genomic annotations. Specific examples are provided that demonstrate why sequence homology alone cannot be relied upon to annotate and classify transporter function, and to show how even single amino acid r

SUBMITTER: David R 

PROVIDER: S-EPMC6758574 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature