Risk assessment and genomic characterization of Zika virus in China and its surrounding areas.

ABSTRACT:

Background

Zika virus (ZIKV) has emerged as a global pathogen causing significant public health concerns. China has reported several imported cases where ZIKV were carried by travelers who frequently travel between China and ZIKV-endemic regions. To fully characterize the ZIKV strains isolated from the cases reported in China and assess the risk of ZIKV transmission in China, comprehensive phylogenetic and genetic analyses were performed both on all ZIKV sequences of China and on a group of scientifically selected ZIKV sequences reported in some of the top interested destinations for Chinese travelers.

Methods

ZIKV genomic sequences were retrieved from the National Center for Biotechnology Information database through stratified sampling. Recombination event detection, maxim

SUBMITTER: Liu RF 

PROVIDER: S-EPMC6759086 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature