Transcatheter aortic valve implantation versus surgical aortic valve replacement in patients at low and intermediate risk: A risk specific meta-analysis of randomized controlled trials.

ABSTRACT: BACKGROUND:Transcatheter aortic valve implantation (TAVI) is an option for treatment for patients with severe aortic stenosis who are at high risk for death with surgical aortic valve replacement (SAVR). It is unknown whether TAVI can be safely introduced to intermediate- and low-risk patients. OBJECTIVE:To compare the efficacy and safety of TAVI and SAVR in patients with intermediate- and low-surgical risk. DATA SOURCES:Medline, Embase, and the Cochrane Central Register of Controlled Trials were searched from inception to April 15, 2019. STUDY SELECTION:We included randomized controlled trials comparing TAVI with SAVR in patients with intermediate- and low-surgical risk. DATA EXTRACTION:Meta-analyses were conducted using random-effects models to calculate risk ratios (RR) with correspondi

SUBMITTER: Fang F 

PROVIDER: S-EPMC6759164 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature