Role of Dietary Flavonoid Compounds in Driving Patterns of Microbial Community Assembly.

ABSTRACT: Flavonoids are a group of polyphenolic dietary compounds found in many different plant-based foods. There is increasing evidence that higher flavonoid intake may be causally linked to a reduced risk of cardiovascular disease and other chronic diseases. The bioactivity and bioavailability of many dietary flavonoids can be influenced by gastrointestinal microbiome metabolism. However, the role that habitual flavonoid intake plays in shaping the human gut microbiome is poorly understood. We describe an application of an ecosystem-based analytic approach to nutritional, microbiome, and questionnaire data from a cohort of more than 240 generally healthy adult males to assess the role of dietary flavonoid compounds in driving patterns of microbial community assembly. We identified six subclass-s

SUBMITTER: Ivey KL 

PROVIDER: S-EPMC6759757 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature