Maternal polycystic ovarian syndrome and offspring growth: the Upstate KIDS Study.

ABSTRACT:

Background

Polycystic ovarian syndrome (PCOS) is the most common cause of female infertility and is associated with higher levels of circulating androgens. Exposure to higher levels of androgens in utero may be a risk factor for obesity among children of women with PCOS.

Methods

We examined whether maternal PCOS was associated with differences in offspring growth and obesity in the Upstate KIDS study, a prospective cohort study of infants born in New York State (excluding New York City) oversampled for fertility treatments and multiple births. Measurements of offspring length/height and weight were recorded at doctor's visits through 3 years of age. PCOS diagnosis was self-reported by mothers at baseline. We used linear mixed models with robust SEs to estimate differences in

SUBMITTER: Bell GA 

PROVIDER: S-EPMC6759926 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature