Association Between Hypertension and Kidney Function Decline: The Atherosclerosis Risk in Communities (ARIC) Study.

ABSTRACT:

Rationale & objective

The relationship between hypertension, antihypertension medication use, and change in glomerular filtration rate (GFR) over time among individuals with preserved GFR requires investigation.

Study design

Observational study.

Setting & participants

14,854 participants from the Atherosclerosis Risk in Communities (ARIC) Study.

Predictors

Baseline hypertension status (1987-1989) was categorized according to the 2017 American College of Cardiology/American Heart Association Clinical Practice Guideline as normal blood pressure, elevated blood pressure, stage 1 hypertension, stage 2 hypertension without medication, or stage 2 hypertension with medication.

Outcomes

Slope of estimated GFR (eGFR) at 5 study visits over 30 years.

Analytical

SUBMITTER: Yu Z 

PROVIDER: S-EPMC6760841 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature