Survival of infants ≤24 months of age with brain tumors: A population-based study using the SEER database.

ABSTRACT: INTRODUCTION:Brain tumors are the most common solid malignancy and leading cause of cancer-related deaths in infants. Current epidemiological data is limited by low numbers of reported cases. This study used a population-based approach with analysis of contemporary and historical survival curves to provide up-to-date prognostication. METHODS:Observational cohort analysis was performed using the Surveillance, Epidemiology and End Results (SEER) database. Infants with brain tumors diagnosed from 1973 to 2013 were categorized by the most common tumor types (diffuse astrocytic and oligodendroglioma, choroid plexus, embryonal, ependymal, medulloblastoma and pilocytic astrocytoma). The 1, 5 and 10 year survival was stratified by decade, with trends in management and outcomes analyzed. RESULTS:We

SUBMITTER: Faltermeier C 

PROVIDER: S-EPMC6760899 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature