Relationship between the lipid composition of maternal plasma and infant plasma through breast milk.

ABSTRACT: INTRODUCTION:This study was motivated by the report that infant development correlates with particular lipids in infant plasma. OBJECTIVE:The hypothesis was that the abundance of these candidate biomarkers is influenced by the dietary intake of the infant. METHODS:A cohort of 30 exclusively-breastfeeding mother-infant pairs from a small region of West Africa was used for this observational study. Plasma and milk from the mother and plasma from her infant were collected within 24 h, 3 months post partum. The lipid, sterol and glyceride composition was surveyed using direct infusion MS in positive and negative ion modes. Analysis employed a combination of univariate and multivariate tests. RESULTS:The lipid profiles of mother and infant plasma samples are similar but distinguishable, and bot

SUBMITTER: Furse S 

PROVIDER: S-EPMC6761246 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature