A Chemical Approach to Optimizing Bioactive Glass Dental Composites.

ABSTRACT: The chemical microenvironment surrounding dental composites plays a crucial role in controlling the bacteria grown on these specialized surfaces. In this study, we report a scanning electrochemical microscopy (SECM)-based analytic technique to design and optimize metal ion-releasing bioactive glass (BAG) composites, which showed a significant reduction in biofilm growth. SECM allows positioning of the probe without touching the substrate while mapping the chemical parameters in 3-dimensional space above the substrate. Using SECM and a solid-state H⁺ and Ca²⁺ ion-selective microprobe, we determined that the local Ca²⁺ concentration released by different composites was 10 to 224 µM for a BAG particle size of <5 to 150 µm in the presence of artificial saliva a

SUBMITTER: Aponso S 

PROVIDER: S-EPMC6761734 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature