Specific Vaginal Bacteria Are Associated With an Increased Risk of Trichomonas vaginalis Acquisition in Women.

ABSTRACT:

Background

While bacterial vaginosis has been associated with an increased risk of Trichomonas vaginalis (TV) acquisition, it is unknown whether other characteristics of the vaginal microbiota, including the presence of key bacterial species, influence a woman's risk of TV acquisition.

Methods

The vaginal microbiota before 25 unique episodes of TV infection involving 18 women was compared to that of 50 controls who remained uninfected. TV was detected by transcription-mediated amplification. Vaginal microbiota were quantified using broad-range polymerase chain reaction analysis and taxon-specific quantitative PCR of the 16S ribosomal RNA gene.

Results

TV acquisition was significantly associated with the presence of Prevotella amnii (risk ratio [RR], 2.21; 95% confiden

SUBMITTER: Jarrett OD 

PROVIDER: S-EPMC6761949 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature