Validating a popular outpatient antibiotic database to reliably identify high prescribing physicians for patients 65 years of age and older.

ABSTRACT:

Objective

Many jurisdictions lack comprehensive population-based antibiotic use data and rely on third party companies, most commonly IQVIA. Our objective was to validate the accuracy of the IQVIA Xponent antibiotic database in identifying high prescribing physicians compared to the reference standard of a highly accurate population-wide database of outpatient antimicrobial dispensing for patients ≥65 years.

Methods

We conducted this study between 1 March 2016 and 28 February 2017 in Ontario, Canada. We evaluated the agreement and correlation between the databases using kappa statistics and Bland-Altman plots. We also assessed performance characteristics for Xponent to accurately identify high prescribing physicians with sensitivity, specificity, positive predictive value (P

SUBMITTER: Schwartz KL 

PROVIDER: S-EPMC6762161 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature