Ontology highlight
ABSTRACT:
SUBMITTER: Sato A
PROVIDER: S-EPMC6763415 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Journal of neuro-oncology 20170310 2
Approximately half of surgically-treated patients with low-grade-glioma (LGG) suffer recurrence or metastasis. Currently there is no effective drug treatment. While the selective COX-2 inhibitor celecoxib showed anti-neoplastic activity against several malignant tumors, its effects against LGG remain to be elucidated. Ours is the first report that the expression level of COX-2 in brain tissue samples from patients with LGG and in LGG cell lines is higher than in the non-neoplastic region and in ...[more]