Effects of Flavanol-Rich Dark Chocolate on Visual Function and Retinal Perfusion Measured With Optical Coherence Tomography Angiography: A Randomized Clinical Trial.

ABSTRACT:

Importance

A recently reported randomized clinical trial suggested beneficial effects of vasodilating flavanols in dark chocolate on visual function without objective quantification of retinal perfusion.

Objective

To assess the effects of dark chocolate flavanols on subjective visual function and retinal perfusion objectively quantified on optical coherence tomography (OCT) angiography.

Design, setting, and participants

This randomized, masked double-blind crossover clinical trial analyzed 22 healthy participants at the Department of Ophthalmology, Ludwig-Maximilians-University Munich, Germany, in July 2018. Analysis was intention to treat. Analysis began in July 2018.

Interventions

Participants were randomized to consume 20 g of dark chocolate containing 400 m

SUBMITTER: Siedlecki J 

PROVIDER: S-EPMC6763974 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature