Molecular Characterization of Lipoaspirates Used in Regenerative Head and Neck Surgery.

ABSTRACT:

Importance

Adipose-derived mesenchymal stem cells (ASCs) have been used commonly in regenerative medicine and increasingly for head and neck surgical procedures. Lipoaspiration with centrifugation is purported to be a mild method for the extraction of ASCs used for autologous transplants to restore tissue defects or induce wound healing. The content of ASCs, their paracrine potential, and cellular potential in wound healing have not been explored for this method to our knowledge.

Objective

To evaluate the characteristics of lipoaspirates used in reconstructive head and neck surgical procedures with respect to wound healing.

Design, setting, and participants

This case series study included 15 patients who received autologous fat injections in the head and neck during s

SUBMITTER: Sharaf K 

PROVIDER: S-EPMC6764019 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature