Associations of Blood Pressure and Cholesterol Levels During Young Adulthood With Later Cardiovascular Events.

ABSTRACT:

Background

Blood pressure (BP) and cholesterol are major modifiable risk factors for cardiovascular disease (CVD), but effects of exposures during young adulthood on later life CVD risk have not been well quantified.

Objective

The authors sought to evaluate the independent associations between young adult exposures to risk factors and later life CVD risk, accounting for later life exposures.

Methods

The authors pooled data from 6 U.S. cohorts with observations spanning the life course from young adulthood to later life, and imputed risk factor trajectories for low-density lipoprotein (LDL) and high-density lipoprotein cholesterols, systolic and diastolic BP starting from age 18 years for every participant. Time-weighted average exposures to each risk factor during you

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC6764095 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature