Risk of Malignant Cancers in Inflammatory Bowel Disease.

ABSTRACT:

Objectives

To explore the trends and the predictors of incident malignant cancer among patients with inflammatory bowel disease [IBD].

Methods

We identified a cohort of all patients with incident IBD in Quebec, Canada, from 1998 to 2015, using provincial administrative health-care databases [RAMQ and Med-Echo]. Annual incidence rates [IRs] of cancer were calculated using Poisson regression and were compared with those of the Quebec population using standardized incidence ratios [SIRs ]. Temporal trends in these rates were evaluated by fitting generalized linear models. Conditional logistic regression was used to estimate odds ratios [ORs] for predictors associated with cancer development.

Results

The cohort included 35 985 patients with IBD, of which 2275 developed ca

SUBMITTER: Loo SY 

PROVIDER: S-EPMC6764102 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature