Enzyme-Powered Nanomotors with Controlled Size for Biomedical Applications.

ABSTRACT: Self-propelled motors have been developed with promising potential for medical applications. However, most of them have a size range at the microscale, which limits their further research for in vivo experiments. Previously, our group developed nanoscaled motors with a size of around 400 nm with several merits, for example, delivering both hydrophobic and hydrophilic drugs/proteins, using biocompatible fuels while being able to control their motion, and showing adaptive changes of their speed and navigation to changes in the environment. It is also well-known that nanoparticles that are around 20-200 nm in size have advantages in overcoming cellular barriers and being internalized into cells. Therefore, lowering the size range of this stomatocyte nanomotor is crucial. However, the s

SUBMITTER: Sun J 

PROVIDER: S-EPMC6764168 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature