A case report of Histoplasma capsulatum prosthetic valve endocarditis: an extremely rare presentation with characteristic findings.

ABSTRACT:

Background

Histoplasma capsulatum is an extremely rare cause of prosthetic valve endocarditis (PVE) and can present with non-specific symptoms leading to a delay in diagnosis with unfavourable outcomes.

Case summary

A 65-year-old male patient with a history of a bioprosthetic aortic valve replacement and non-obstructive coronary artery disease was admitted for altered mentation, failure to thrive, and a 20-pound unintentional weight loss over the past 4 months. Upon examination, he was lethargic but afebrile and haemodynamically stable. A late peaking ejection murmur was heard on exam. Skin exam was significant for embolic phenomenon involving the extremities. Inflammatory markers and serum calcium were elevated. A bedside echocardiogram showed severe obstruction acro

SUBMITTER: Adigun RO 

PROVIDER: S-EPMC6764570 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature