Radial variation in biochemical composition of the bovine caudal intervertebral disc.

ABSTRACT: Bovine caudal discs have been widely used in spine research due to their increased availability, large size, and mechanical and biochemical properties that are comparable to healthy human discs. However, despite their extensive use, the radial variations in bovine disc composition have not yet been rigorously quantified with high spatial resolution. Previous studies were limited to qualitative analyses or provided limited spatial resolution in biochemical properties. Thus, the main objective of this study was to provide quantitative measurements of biochemical composition with higher spatial resolution than previous studies that employed traditional biochemical techniques. Specifically, traditional biochemical analyses were used to measure water, sulfated glycosaminoglycan, collagen, and D

SUBMITTER: Bezci SE 

PROVIDER: S-EPMC6764789 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature