An in silico investigation of menthol metabolism.
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ABSTRACT:
SUBMITTER: Limpanuparb T
PROVIDER: S-EPMC6764827 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
An in silico investigation of menthol metabolism.
Limpanuparb Taweetham T Lorpaiboon Wanutcha W Chinsukserm Kridtin K
PloS one 20190927 9
Prevalence of mentholated products for consumption has brought great importance to studies on menthol's metabolic pathways to ensure safety, design more potent derivatives, and identify therapeutic benefits. Proposed pathways of (-)-menthol metabolism based on metabolites found experimentally in previous works by Yamaguchi, Caldwell & Farmer, Madyastha & Srivatsan and Hiki et al. were not in agreement. This in silico approach is based on the three in vivo studies and aims to resolve the discrepa ...[more]
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