Lifetime surgical exposure, episodic memory, and forniceal microstructure in older adults.

ABSTRACT: Introduction: Aging is associated with heterogeneous cognitive trajectories. There is considerable interest in identifying risk factors for pathological aging, with recent studies demonstrating a link between surgical procedures and proximal cognitive decline; however, the role of lifetime exposure to surgical procedures and cognitive function has been relatively unexplored. This pilot study aimed to evaluate the association between total lifetime surgical procedures and memory function in older adults. Methods: A cohort of 62 older adults underwent a neuropsychological evaluation and health history assessment. Self-reported lifetime surgical history was categorized as "cardiac" or "non-cardiac." General linear models were fit with demographics as nuisance covariates, and the

SUBMITTER: Bateman JR 

PROVIDER: S-EPMC6764849 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature