Cortisol and adrenocorticotropic hormone concentrations in horses with systemic inflammatory response syndrome.

ABSTRACT:

Background

Plasma adrenocorticotropic hormone (ACTH) and serum cortisol concentrations increase with illness-associated stress. Dynamics of plasma ACTH and serum cortisol concentrations in adult horses with systemic illness are undocumented.

Hypothesis/objective

To determine whether ACTH and cortisol concentrations and the ACTH/cortisol ratio vary with survival, the presence of systemic inflammatory response syndrome (SIRS), or ischemic gastrointestinal lesions at admission, or throughout hospitalization.

Animals

One hundred fifty-one adult horses.

Methods

Prospective study measuring serum cortisol and plasma ACTH at admission and on days 2, 4, and 6 of hospitalization. Horses were grouped by outcome (survival, SIRS status, number of SIRS criteria [SIRS score],

SUBMITTER: Stewart AJ 

PROVIDER: S-EPMC6766528 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature