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Porcine placental extract facilitates memory and learning in aged mice.


ABSTRACT: Aging induces a decline in both memory and learning ability without predisposing an individual to diseases of the central nervous system, such as dementia. This decline can have a variety of adverse effects on daily life, and it can also gradually affect the individual and the people they are surrounded by. Since recent evidence indicated that placental extract has effects on brain function such as memory, we hypothesized that placental extract could ameliorate the age-associated reduction in cognitive function in aging. Here, we investigated the effect of new modified porcine placental extract (SD-F) on memory ability in aged mice at both the behavioral and molecular levels. Our results revealed that SD-F significantly enhanced memory ability in the object recognition and object location

SUBMITTER: Yamauchi A 

PROVIDER: S-EPMC6766592 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature