EVEREST study report 4: Fluorescein angiography features predictive of polypoidal choroidal vasculopathy.

ABSTRACT:

Importance

It is important to identify features of polypoidal choroidal vasculopathy (PCV) that differentiate it from typical neovascular age-related macular degeneration (nAMD) on various imaging modalities, including fluorescein angiography (FA).

Background

PCV was thought to be indistinguishable from nAMD using FA alone. In real-world practice, indocyanine-green angiography may often be unavailable or contraindicated.

Design

Analysis of FA images from a prospective, multicentre study.

Participants

Study images of both PCV and nAMD patients from the EVEREST study.

Methods

FA features at baseline were independently graded by masked graders (fellowship-trained ophthalmologists) using standardized diagnostic algorithms.

Main outcome measures

Predic

SUBMITTER: Tan CS 

PROVIDER: S-EPMC6767036 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature