Therapeutic value of steroidal alkaloids in cancer: Current trends and future perspectives.

ABSTRACT: Discovery and development of new potentially selective anticancer agents are necessary to prevent a global cancer health crisis. Currently, alternative medicinal agents derived from plants have been extensively investigated to develop anticancer drugs with fewer adverse effects. Among them, steroidal alkaloids are conventional secondary metabolites that comprise an important class of natural products found in plants, marine organisms and invertebrates, and constitute a judicious choice as potential anti-cancer leads. Traditional medicine and modern science have shown that representatives from this compound group possess potential antimicrobial, analgesic, anticancer and anti-inflammatory effects. Therefore, systematic and recapitulated information about the bioactivity of these compounds,

SUBMITTER: Dey P 

PROVIDER: S-EPMC6767045 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature