Differentiating supraclavicular from gluteal adipose tissue based on simultaneous PDFF and T2 * mapping using a 20-echo gradient-echo acquisition.

ABSTRACT: BACKGROUND:Adipose tissue (AT) can be classified into white and brown/beige subtypes. Chemical shift encoding-based water-fat MRI-techniques allowing simultaneous mapping of proton density fat fraction (PDFF) and T2 * result in a lower PDFF and a shorter T2 * in brown compared with white AT. However, AT T2 * values vary widely in the literature and are primarily based on 6-echo data. Increasing the number of echoes in a multiecho gradient-echo acquisition is expected to increase the precision of AT T2 * mapping. PURPOSE:1) To mitigate issues of current T2 *-measurement techniques through experimental design, and 2) to investigate gluteal and supraclavicular AT T2 * and PDFF and their relationship using a 20-echo gradient-echo acquisition. STUDY TYPE:Prospective. SUBJECTS:Twenty-one healthy

SUBMITTER: Franz D 

PROVIDER: S-EPMC6767392 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature