Mixed-methods approach to exploring patients' perspectives on the acceptability of a urinary biomarker test in replacing cystoscopy for bladder cancer surveillance.

ABSTRACT:

Objectives

To determine the minimal accepted sensitivity (MAS) of a urine biomarker that patients are willing to accept to replace cystoscopy and to assess qualitatively their views and reasons.

Patients and methods

Patients were part of a prospective multicentre observational study recruiting people with bladder cancer for a urine biomarker study (DETECT II; ClinicalTrials.gov: NCT02781428). A mixed-methods approach comprising (1) a questionnaire to assess patients' experience with cystoscopy and patients' preference for cystoscopy vs urinary biomarker, and (2) semi-structured interviews to understand patient views, choice and reasons for their preference.

Results

A urine biomarker with an MAS of 90% would be accepted by 75.8% of patients. This was despite a high sel

SUBMITTER: Tan WS 

PROVIDER: S-EPMC6767410 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature