Mind the gap: resources required to receive, process and interpret research-returned whole genome data.

ABSTRACT: Most genotype-phenotype studies have historically lacked population diversity, impacting the generalizability of findings and thereby limiting the ability to equitably implement precision medicine. This well-documented problem has generated much interest in the ascertainment of new cohorts with an emphasis on multiple dimensions of diversity, including race/ethnicity, gender, age, socioeconomic status, disability, and geography. The most well known of these new cohort efforts is arguably All of Us, formerly known as the Precision Medicine Cohort Initiative Program. All of Us intends to ascertain at least one million participants in the United States representative of the multiple dimensions of diversity. As an incentive to participate, All of Us is offering the return of research results,

SUBMITTER: Crawford DC 

PROVIDER: S-EPMC6767905 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature