DecoyDeveloper: An On-Demand, De Novo Decoy Glycopeptide Generator.

ABSTRACT: Glycopeptide analysis is a growing field that is struggling to adopt effective, automated tools. Many creative workflows and software apps have emerged recently that offer promising capabilities for assigning glycopeptides to MS data in an automated fashion. The effectiveness of these tools is best measured and improved by determining how often they would select a glycopeptide decoy as a spectral match, instead of its correct assignment; yet generating the appropriate number and type of glycopeptide decoys can be challenging. To address this need, we have designed DecoyDeveloper, an on-demand decoy glycopeptide generator that can produce a high volume of decoys with low mass differences. DecoyDeveloper has a simple user interface and is capable of producing large sets of decoys containing

SUBMITTER: Shipman JT 

PROVIDER: S-EPMC6768553 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature