Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia.

ABSTRACT:

Background

Gestational trophoblastic neoplasia (GTN) is a highly curable group of pregnancy-related tumours; however, approximately 25% of GTN tumours will be resistant to, or will relapse after, initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. Various salvage regimens are used worldwide. It is unclear which regimens are the most effective and the least toxic.

Objectives

To determine which chemotherapy regimen/s for the treatment of resistant or relapsed GTN is/are the most effective and the least toxic.

Search methods

We searched the Cochrane Gynaecological Cancer Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL, Issue 4), MEDLINE and EMBASE up to October 2011.

SUBMITTER: Alazzam M 

PROVIDER: S-EPMC6768657 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature