Distinct patterns of natural selection determine sub-population structure in the fire blight pathogen, Erwinia amylovora.

ABSTRACT: The fire blight pathogen, Erwinia amylovora (EA), causes significant economic losses in rosaceae fruit crops. Recent genome sequencing efforts have explored genetic variation, population structure, and virulence levels in EA strains. However, the genomic aspects of population bottlenecks and selection pressure from geographical isolation, host range, and management practices are yet unexplored. We conducted a comprehensive analysis of whole genome sequences of 41 strains to study genetic diversity, population structure, and the nature of selection affecting sub-population differentiation in EA. We detected 72,741 SNPs and 2,500 Indels, representing about six-fold more diversity than previous reports. Moreover, nonsynonymous substitutions were identified across the effector regions, suggest

SUBMITTER: Singh J 

PROVIDER: S-EPMC6768868 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature