Evaluation of heat stress and cumulative incidence of acute kidney injury in sugarcane workers in Guatemala.

ABSTRACT:

Objective

Agricultural workers worldwide exposed to heat stress could be at the risk of kidney injury, which could lead to chronic kidney disease of an unknown origin (CKDu). Hydration has been promoted as a key measure to reduce kidney injury. In the presence of a hydration intervention, the incidence of acute kidney injury (AKI) was calculated in a sugarcane worker population in Guatemala and several risk factors were evaluated.

Methods

We measured kidney function at the beginning and end of the work shift at three time points in 517 sugarcane workers. We defined AKI as an increase in serum creatinine of 26.5 µmol/L or 50% or more from the pre-shift value. Associations between AKI and risk factors were examined, including interactions with hydration status.

Results

SUBMITTER: Butler-Dawson J 

PROVIDER: S-EPMC6768910 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature