IS26-Mediated Genetic Rearrangements in Salmonella Genomic Island 1 of Proteus mirabilis.

ABSTRACT: Salmonella genomic island 1 (SGI1) is an integrative mobilizable element integrated into the chromosome of bacteria, which plays an important role in the dissemination of antimicrobial resistance genes. Lots of SGI1 variants are found mainly in Salmonella enterica and Proteus mirabilis. In this study, a total of 157 S. enterica and 132 P. mirabilis strains were collected from food-producing animals in Sichuan Province of China between December 2016 and November 2017. Detection of the SGI1 integrase gene showed that three S. enterica and five P. mirabilis strains were positive for SGI1, which displayed different multidrug resistance profiles. Five different SGI1 variants, including two novel variants (SGI1-PmBC1123 and SGI1-PmSC1111), were ch

SUBMITTER: Wang XC 

PROVIDER: S-EPMC6769106 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature