Oct-4: a prognostic biomarker of urinary bladder cancer in North India.

ABSTRACT:

Background

The objective of this study was to evaluate Octamer-binding transcription factor 4 (Oct-4), neutrophil to lymphocyte ratio (NLR) and body mass index (BMI) as independent prognostic biomarkers for prediction of urinary bladder cancer (UBC) outcomes. With the advancement in prognostic biomarker discovery, tumor recurrence is difficult to accurately predict in UBC. UBC is costly to treat due to the requirement of frequent invasive follow-up sessions. Therefore, it is of utmost importance to evaluate good prognostic biomarkers for UBC surveillance.

Methods

We studied 39 UBC tissue samples. Oct-4 protein expression was evaluated semiquantitatively by immunohistochemistry (IHC). Complete blood count data and body weight as well as the height of the patients were retriev

SUBMITTER: Siddiqui Z 

PROVIDER: S-EPMC6769204 | biostudies-literature | 2019 Jan-Dec

REPOSITORIES: biostudies-literature