The avalanche-like behaviour of large-scale haemodynamic activity from wakefulness to deep sleep.

ABSTRACT: Increasing evidence suggests that responsiveness is associated with critical or near-critical cortical dynamics, which exhibit scale-free cascades of spatio-temporal activity. These cascades, or 'avalanches', have been detected at multiple scales, from in vitro and in vivo microcircuits to voltage imaging and brain-wide functional magnetic resonance imaging (fMRI) recordings. Criticality endows the cortex with certain information-processing capacities postulated as necessary for conscious wakefulness, yet it remains unknown how unresponsiveness impacts on the avalanche-like behaviour of large-scale human haemodynamic activity. We observed a scale-free hierarchy of co-activated connected clusters by applying a point-process transformation to fMRI data recorded during wakefulne

SUBMITTER: Bocaccio H 

PROVIDER: S-EPMC6769314 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature