Evolutionary Rate Heterogeneity and Functional Divergence of Orthologous Genes in Pyrus.

ABSTRACT: Negatively selected genes (NSGs) and positively selected genes (PSGs) are the two types of most nuclear protein-coding genes in organisms. However, the evolutionary rates and characteristics of different types of genes have been rarely understood. In the present study, we investigate the rates of synonymous substitution (Ks) and the rates of non-synonymous substitution (Ka) by comparing the orthologous genes of two sequenced Pyrus species, Pyrus bretschneideri and Pyrus communis. Subsequently, we compared the evolutionary rates, gene structures, and expression profiles during different fruit development between PSGs and NSGs. Compared with the NSGs, the PSGs have fewer exons, shorter gene length, lower synonymous substitution rates and have higher evolutionary rates. R

SUBMITTER: Cao Y 

PROVIDER: S-EPMC6770726 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature