Proteome Profiling of the Exhaled Breath Condensate after Long-Term Spaceflights.

ABSTRACT: Comprehensive studies of the effects of prolonged exposure to space conditions and the overload experienced during landing on physiological and biochemical changes in the human body are extremely important in the context of planning long-distance space flights, which can be associated with constant overloads and various risk factors for significant physiological changes. Exhaled breath condensate (EBC) can be considered as a valuable subject for monitoring physiological changes and is more suitable for long-term storage than traditional monitoring subjects such as blood and urine. Herein, the EBC proteome changes due to the effects of spaceflight factors are analyzed. Thirteen EBC samples were collected from five Russian cosmonauts (i) one month before flight (background), (ii) immediately

SUBMITTER: Kononikhin AS 

PROVIDER: S-EPMC6770753 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature