α-Arylation of Carbonyl Compounds through Oxidative C-C Bond Activation.

ABSTRACT: A synthetically useful approach for the direct α-arylation of carbonyl compounds through a novel oxidative C-C bond activation is reported. This mechanistically unusual process relies on a 1,2-aryl shift and results in all-carbon quaternary centers. The transformation displays broad functional-group tolerance and can in principle also be applied as an asymmetric variant.

SUBMITTER: Li J 

PROVIDER: S-EPMC6771532 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature