Multicenter validation of automated trajectories for selective laser amygdalohippocampectomy.

ABSTRACT:

Objective

Laser interstitial thermal therapy (LITT) is a novel minimally invasive alternative to open mesial temporal resection in drug-resistant mesial temporal lobe epilepsy (MTLE). The safety and efficacy of the procedure are dependent on the preplanned trajectory and the extent of the planned ablation achieved. Ablation of the mesial hippocampal head has been suggested to be an independent predictor of seizure freedom, whereas sparing of collateral structures is thought to result in improved neuropsychological outcomes. We aim to validate an automated trajectory planning platform against manually planned trajectories to objectively standardize the process.

Methods

Using the EpiNav platform, we compare automated trajectory planning parameters derived from expert opinion a

SUBMITTER: Vakharia VN 

PROVIDER: S-EPMC6771574 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature