Nerve ultrasound can identify treatment-responsive chronic neuropathies without electrodiagnostic features of demyelination.

ABSTRACT:

Introduction

We present a case series of six treatment-naive patients with clinical phenotypes compatible with chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy without electrodiagnostic features of demyelination but with abnormal peripheral ultrasound findings who responded to treatment.

Methods

All six patients underwent a complete set of ancillary investigations, including extensive nerve conduction studies. We also performed standardized nerve ultrasound of median nerves and brachial plexus as part of a larger effort to evaluate diagnostic value of sonography.

Results

Nerve conduction studies did not show conduction block or other signs of demyelination in any of the six patients. Sonographic nerve enlargement was present in all pat

SUBMITTER: Goedee HS 

PROVIDER: S-EPMC6771613 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature