Saliva cotinine concentrations in pregnant women who smoke and use nicotine patches.

ABSTRACT:

Background and aims

Due to concerns about increased exposure to nicotine, pregnant women using nicotine replacement therapy (NRT) to stop smoking are usually advised to stop using NRT if they relapse to smoking. This study investigated whether this is justified. We compared changes in saliva cotinine from baseline to 2 weeks post-target quit date pregnant smokers who relapsed to smoking and continued to use their patches having been assigned to use nicotine patches or placebo.

Design and setting

Controlled pre-post design stratified by intervention condition from the 'Study of Nicotine Patch in Pregnancy', a randomized, placebo-controlled trial.

Participants

A sample of 268 pregnant women, assigned placebo (n = 122) or nicotine (n = 146) patches, who returned for furt

SUBMITTER: Claire R 

PROVIDER: S-EPMC6771792 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature