Developmental Changes in Task-Induced Brain Deactivation in Humans Revealed by a Motor Task.

ABSTRACT: Performing tasks activates relevant brain regions in adults while deactivating task-irrelevant regions. Here, using a well-controlled motor task, we explored how deactivation is shaped during typical human development and whether deactivation is related to task performance. Healthy right-handed children (8-11 years), adolescents (12-15 years), and young adults (20-24 years; 20 per group) underwent functional magnetic resonance imaging with their eyes closed while performing a repetitive button-press task with their right index finger in synchronization with a 1-Hz sound. Deactivation in the ipsilateral sensorimotor cortex (SM1), bilateral visual and auditory (cross-modal) areas, and bilateral default mode network (DMN) progressed with development. Specifically, ipsilateral SM1 and lateral

SUBMITTER: Morita T 

PROVIDER: S-EPMC6771882 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature