Identification of key candidate genes and pathways in multiple myeloma by integrated bioinformatics analysis.
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ABSTRACT:
SUBMITTER: Yan H
PROVIDER: S-EPMC6771956 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
Identification of key candidate genes and pathways in multiple myeloma by integrated bioinformatics analysis.
Yan Haimeng H Zheng Gaofeng G Qu Jianwei J Liu Yang Y Huang Xi X Zhang Enfan E Cai Zhen Z
Journal of cellular physiology 20190618 12
Multiple myeloma (MM) is a common hematologic malignancy for which the underlying molecular mechanisms remain largely unclear. This study aimed to elucidate key candidate genes and pathways in MM by integrated bioinformatics analysis. Expression profiles GSE6477 and GSE47552 were obtained from the Gene Expression Omnibus database, and differentially expressed genes (DEGs) with p < .05 and [logFC] > 1 were identified. Functional enrichment, protein-protein interaction network construction and sur ...[more]
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