Type 2 diabetes remission 1 year after an intensive lifestyle intervention: A secondary analysis of a randomized clinical trial.

ABSTRACT:

Aim

To investigate whether an intensive lifestyle intervention induces partial or complete type 2 diabetes (T2D) remission.

Materials and methods

In a secondary analysis of a randomized, assessor-blinded, single-centre trial, people with non-insulin-dependent T2D (duration <10 years), were randomly assigned (2:1, stratified by sex, from April 2015 to August 2016) to a lifestyle intervention group (n = 64) or a standard care group (n = 34). The primary outcome was partial or complete T2D remission, defined as non-diabetic glycaemia with no glucose-lowering medication at the outcome assessments at both 12 and 24 months from baseline. All participants received standard care, with standardized, blinded, target-driven medical therapy during the initial 12 months. The lifestyle in

SUBMITTER: Ried-Larsen M 

PROVIDER: S-EPMC6772176 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature