Ontology highlight
ABSTRACT:
SUBMITTER: Sahoo B
PROVIDER: S-EPMC6773098 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Sahoo Basudev B Bellotti Peter P Juliá-Hernández Francisco F Meng Qing-Yuan QY Crespi Stefano S König Burkhard B Martin Ruben R
Chemistry (Weinheim an der Bergstrasse, Germany) 20190606 38
A photoinduced carboxylation of alkyl halides with CO<sub>2</sub> at remote sp<sup>3</sup> C-H sites enabled by the merger of photoredox and Ni catalysis is described. This protocol features a predictable reactivity and site selectivity that can be modulated by the ligand backbone. Preliminary studies reinforce a rationale based on a dynamic displacement of the catalyst throughout the alkyl side chain. ...[more]