Rationale and population-based prospective cohort protocol for the disadvantaged populations at risk of decline in eGFR (CO-DEGREE).

ABSTRACT:

Introduction

A recently recognised form of chronic kidney disease (CKD) of unknown origin (CKDu) is afflicting communities, mostly in rural areas in several regions of the world. Prevalence studies are being conducted in a number of countries, using a standardised protocol, to estimate the distribution of estimated glomerular filtration rate (eGFR), and thus identify communities with a high prevalence of reduced glomerular filtration rate (GFR). In this paper, we propose a standardised minimum protocol for cohort studies in high-risk communities aimed at investigating the incidence of, and risk factors for, early kidney dysfunction.

Methods and analysis

This generic cohort protocol provides the information to establish a prospective population-based cohort study in low-incom

SUBMITTER: Gonzalez-Quiroz M 

PROVIDER: S-EPMC6773312 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature